Medtronic Studies Drug-Eluting Stent Safety

Medtronic Inc. is beginning a large, randomized trial that will examine the safety of drug-eluting stents. The 8800-patient clinical trial will compare the company's zotarolimus-eluting coronary stent system (Endeavor) with J&J's sirolimus-eluting stent (Cypher). Medtronic enrolled the first patient in the study, called Protect, yesterday. The trial will look at overal stent thrombosis after three years.

May 22, 2007

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Other points of analysis will include a composite of death and nonfatal myocardial infarction. According to an investigator of the study, the trial is designed to give doctors the long term safety data that they've been needing.

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