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Growing with a Difference

NuVasive's Alexis V. Lukianov on building a new competitor in medtech's heated spine sector.

COVER STORY

Sidebars:

For a start-up medical device operation to compete effectively in a mature product sector dominated by established industry giants, the company must have not only a promising technology base, but also experienced executives who know how to maximize market penetration. Under the leadership of chairman and CEO Alexis V. Lukianov, NuVasive Inc. (San Diego) has both.

Founded with the vision of redefining the minimally invasive spine surgery market, NuVasive's evolution from a niche player to a noteworthy competitor in the spine sector was especially evident during 2006. During the year, NuVasive generated total annual revenues of $98.1 million, representing a year-over-year increase of 57%. Further, the company launched nine new products, and was able to initiate enrollment for its NeoDisc clinical trial ahead of schedule.

The company also surpassed its goals for training surgeons and developing an exclusive sales force. During 2006, NuVasive trained more than 500 surgeons on its maximum access surgery (MAS) platform and grew its sales force to more than 200 professionals.

Throughout 2007, NuVasive plans to continue its rapid pace of revenue growth and technology development. The company is forecasting year-over-year revenue growth of greater than 40% and expects to turn the corner into profitability this year. The company also plans to increase the breadth and depth of its existing product offerings through a series of strategic launches.

In this interview with MX editor-in-chief Steve Halasey, Lukianov discusses his company's strategy for growing into a strong competitor in medtech's heated spine sector.

MX: How did NuVasive get its start?

Alexis V. Lukianov: NuVasive was founded by a local orthopedic surgeon who was not an expert in the spine arena. He actually had more of a background in sports medicine. He came up with the concept of marrying neurophysiology together with spinal instrumentation. And basically what that means is, he came up with the idea of how to make instruments smart so that they can detect nerves and safely penetrate the pathology.

The surgeon was able to obtain some initial seed funding from a local venture capitalist (VC) who represented Enterprise Partners. That came about, literally, as the result of a conversation during a kids' soccer match. After hearing about the concept, the VC decided to provide some seed capital. And subsequently Enterprise Partners and Kleiner Perkins got involved.

How was it that information about this new company came to you?

Enterprise Partners had done a lot of deals with Kleiner Perkins, so they brought that firm into the deal as well. And that, finally, was what led to my involvement with the company. I was recruited to come here by Kleiner Perkins.

Where were you at the time?

I had previously been president of Medtronic Sofamor Danek USA for several years. When I left the company, I had a three-year noncompete agreement that prevented me from being active in spine devices in particular. So I started a small company in the physician practice management arena that was focused on spine surgeries, which I subsequently sold to a Robert Bass company.

Around the time that my noncompete agreement came to an end, I started getting phone calls from a number of different companies and their headhunters. And that's when, most notably, the Kleiner Perkins opportunity came around.

So it was almost as if they were biding their time and waiting for you to be free?

I guess. More likely, it was just good timing.

In terms of its intellectual property strengths and market potential, how was NuVasive presented to you, such that you became convinced that this was your next opportunity?

The entire concept was extremely novel. Nobody else was thinking about anything like the marriage of neurophysiology with instruments that NuVasive was proposing. On the IP side, they had done some pretty good work in obtaining freedom-to-operate opinions. And they had put together some preliminary patents.

The whole package looked very encouraging. And what was exciting was not just the marriage of neurophysiology with instruments, but the possibility that this approach could bring about the next Eureka! point in the spine world—that is, a way to bring forward minimally invasive spinal surgery, which had not previously really taken off.

Because I was approached by Kleiner Perkins, it was very clear that the firm wanted to put a chip, so to speak, into the spine space. That was an area in which the firm had not been previously involved.

I had previously been involved with mostly larger companies. And, of course, I helped to build Medtronic Sofamor Danek and drive that company to a number-one market share. Now it's the world's largest spine company—and an active competitor for NuVasive.

Ultimately, what attracted me to the Kleiner Perkins offer was the opportunity to build the company from the ground up—as a true start-up—and to take it to whatever level I could. For me, that seemed like a terrific opportunity—a chance to build a company from a cultural, philosophical, and ideological standpoint the way that I really wanted to do it.

You mentioned that the original venture capital investors were Enterprise Partners and Kleiner Perkins. When you joined the company in 1999, did you bring on additional VC investors?

That was one of the first things I did. I got Domain Partners involved from the life sciences side, coming on board in what was essentially a Series B funding round. We ultimately brought in a series of different VCs over the next three years, raising a total of about $72 million in private capital.

We had several strong VC investors. We had Kleiner Perkins, Enterprise Partners, and Domain Partners. We also had a consortium led by William Blair Capital Partners. CDP Capital-Technology Ventures, A.M. Pappas, and Johnson & Johnson Development Corp. also put money into the company.

And then of course we eventually moved forward with our initial public offering (IPO).

What was the trigger for NuVasive deciding to go public in May of 2004?

We had been preparing to take the company public for some time. We felt that the window was open, in terms of getting a reasonable valuation. And I felt confident that the company would be able to perform as it needed to on Wall Street.

The thing that every company worries about as it goes public is the possibility of disappointing investors. As we went public, we were still on somewhat wobbly legs—just as most companies are when they are going through normal growing-pains issues. But frankly, I felt that we were in a good enough position to be able to put forward the kind of revenue that people expected from us.

How did your existing investors advise you with regard to the decision to go public? Were they looking to take their return and move on, or did they want to remain invested in the company?

None of the folks invested in the company were looking for a short-term flip. I think everybody understood that the company had a strong strategic direction, had some terrific products, and had a terrific pipeline. They saw the IPO as just one way to obtain additional capitalization.

Certainly, the IPO was not just an opportunity for the VCs to obtain some liquidity. As you know, VC funds are limited in terms of how long they can stay in a company. Most of the funds run out after 10 years. So, of course, most of the VC funds have eventually distributed over the three years that NuVasive has been public.

But in fact, many of the investors have stuck with us. And I think that they clearly see the upside in the company and its stock.

As NuVasive has grown, how did you go about building your executive team to flesh out the company?

Most of the key executives I brought over were people from Medtronic Sofamor Danek, and others I've known and worked with in the past. And I think that I was able to demonstrate to them that my dream and vision were probably no different than theirs, in terms of being able to build the company the way we would all enjoy seeing it come together.

So what brought these executives on board was an understanding that the technology had promise. But more important was the belief that we could build a top-notch team with the kind of culture that would take us wherever we set our sights on going.

As the location for a start-up medtech company, San Diego offers some great advantages in terms of climate and entrepreneurial attitude. Did you meet with resistance from anybody who just wasn't sure if they wanted to make the move?

I'm a New Yorker myself, and my journey took me through Memphis, where I spent a fair amount of time, and then here to San Diego. I think this is a phenomenal place, and I think the other executives that have come on board feel similarly.

The toughest challenge for San Diego—as with many other places that are fantastic to live in—is that the economics of relocation and the cost of housing are not terribly favorable. And that has certainly put a little bit of a strain on the company over the past few years, in terms of relocating executives. But we've stepped up and done what we have had to do to get the top people.

In general, do you think California's entrepreneurial attitude is helpful to medtech start-ups like NuVasive?

I do, but I also have some mixed feelings on that. Perhaps this is a result of my East Coast bias, but it does seem that the fertile ground of California is only one part of the equation. I've also seen a lot of aggressive and opportunistic people coming here from the East Coast, and they are really driving hard to grow companies.

At our company and a lot of others in California, there's a very strong work ethic. And that reality differs from the stereotypical view that many people have of California. I've found that view to be quite inaccurate.

From what I've seen, these venture-based and entrepreneurial environments work because they offer a good blend of the East and the West.


The Spinal Product Pipeline

Tell me about the core products and procedures that NuVasive was founded on, and how the company has expanded on that base over the years.

Minimally invasive surgery had never really taken off in the spine world, and the reason is that it was technically very challenging. It had been difficult to provide spine surgeons with a safe and reproducible technique that could be performed by the masses of surgeons.

NuVasive's approach of marrying neurophysiology with spinal instrumentation—creating smart instruments that enable the surgeon to navigate down to the spine—opened up a whole new surgical technique. That surgical technique entails being able to come at the spine from the side, versus the traditional approaches, which are from the back (posterior) or from the front (anterior) directions. Coming in from the side with NuVasive's smart instruments—the NeuroVision and neuronavigational technology—enables the surgeon to penetrate to the point of the spinal pathology very quickly.

The next steps make use of an entire suite of NuVasive products designed to prepare the surgical site for a standard fusion procedure. This procedure stops the motion in between the vertebral bodies, which is creating pain, and relieves pressure on the nerves, which causes the pain. The spinal fusion procedure is widely used today for patients that have chronic back pain that has not been resolved by any other means.

In creating its new surgical technique, NuVasive relied on intelligent engineering and significant input from spine surgeons. And those surgeons have been equally excited about the technology and its potential for addressing an area of unmet need in spine surgery.

The technique enables surgeons to perform a fusion procedure 50% faster than before. And it permits patients to recover virtually on the same day and, so far as ambulation is concerned, even within hours after surgery. And, of course, because the technique is significantly faster, it also ends up saving money for the operating room. So it's a hugely significant advance in spine surgery.

And along the way, the surgical technique is reproducible by the masses of spine surgeons, is that correct?

Yes, and that's a key feature. To make this possible, we conduct surgeon training here at our own facility, where we have six operating rooms equipped for cadaver surgeries. Surgeons come here for training, which usually takes just one day. And during that time, they are exposed to the technology and shown how to apply the surgical technique.

In our experience, after surgeons leave here and head home to apply the technology, they get the exact same results as surgeons that have been doing the procedure for the past several years. So there really is not a lengthy learning curve. Once trained, the surgeons are able to perform the surgery and help their patients right away, and they get positive results immediately, right out of the chute.

You alluded to NuVasive's interest in nonfusion techniques. Can you talk a bit about how that is developing?

In developing NuVasive's unique minimally invasive way of accessing the spine, we also realized that we were really providing just a part of the procedure. So about four years ago, we changed our strategy to make sure that we provided the entire technique—and all of the instrumentation to go with it.

Since then, we've come up with a wide range of instruments for performing spinal procedures, including unique forms of retraction and all the different types and sizes of preparation instruments that surgeons need. The whole array would literally cover a large conference table. So we've taken a very comprehensive approach, instead of just offering a couple of instruments.

Taking such a comprehensive perspective has enabled NuVasive to achieve a strong position among the top companies in the field. Even though we are not that big from a market share standpoint, surgeons appreciate that we offer a full scope of products just like the larger companies.

At the same time, we've also been designing more and more products to put through our unique access channels. These have included different types and styles of implants, implants that enable the fusion procedure to work even better and faster, and so on.

Most recently, we've also begun to develop motion preservation products that can be implanted using NuVasive's minimally invasive approach and the resulting access channels. The idea is to use the company's approach, which we call maximum access surgery, to enable surgeons to implant a lumbar total disk replacement or even to work on a patient's neck.

Right now, we are conducting U.S. clinical trials of a product called NeoDisc, which is a nucleus-like total disk replacement. The product consists of a silicone core with embroidery material around it. And it is really intended to replace just the core of the disk.

Over the next several months, we expect to start clinical studies for two other products. The first is the CerPass device, which is another type of motion-preserving implant for the neck, using a ceramic-on-ceramic design. And the second product is the Lateral total disk replacement for the lumbar spine.

NuVasive acquired the NeoDisc product last year from Pearsalls Ltd. (Taunton, UK). How many people are enrolled in the clinical trials for the device, and what is the status of the trials?

The total study involves 500 patients. We are now about 25% of the way through, and we expect to finish the study over the course of the next nine to 12 months—sometime during the first or second quarter of next year.

And after that, how long before the product is likely to be commercially available in the United States?

We need to complete a two-year follow-up on the study patients. So we are figuring about 2010 for possible commercial release, if everything goes well with the clinical trial and FDA process.

We do have CE marking for our products in Europe. And we are adding motion preservation devices to that armamentarium. So, for the international arena, we anticipate launching our extreme lateral interbody fusion (XLIF) technique with motion preservation technologies during the fourth quarter of this year.

So the products will be available in Europe in the fourth quarter of this year?

Yes, but we will not be conducting a full international launch. The key centers we'll be targeting will be mostly the German- and English-speaking countries in Europe. That will be the primary area. But we're also working on our registrations for Japan, so we intend to launch in the Far East a little further in the future.

What is the overall market opportunity for NeoDisc, in terms of number of procedures, or revenue potential?

NeoDisc is intended as an alternative to fusion procedures for the neck. In the United States, approximately 250,000 such procedures are performed each year, with a market value totaling about $1 billion. As this market changes with the advent of motion preservation devices like NeoDisc, we anticipate that somewhere in the neighborhood of 40% of the current number of fusion procedures will move toward motion preservation. So, in other words, the market opportunity is somewhere around $400 million.

I see NeoDisc as the kind of product that is so unique that it has a good chance of capturing a significant portion of that opportunity very rapidly following its U.S. launch.

Will the NeoDisc help to expand the market by overcoming patient resistance to surgical treatment?

I think it could. Over the short term, I think NeoDisc could help to expand the market by 10% or more, assuming the clinical trial goes well and the device is approved for sale in the United States.

One reason for this is that the availability of NeoDisc could lead to earlier intervention. Degenerative disk disease is a type of arthritis, and for most patients the degeneration cascade process continues on unless some treatment intervenes. If patients see a product that can be implanted earlier to address their symptoms, they may be more likely to opt for surgery.

In addition, NeoDisc is designed to be easily removed, and revised. If it turns out that the patient requires a fusion procedure, that can still be performed because the device is designed to not cause fusion.

All of this makes it possible for patients to get the benefit of opening up the disk space earlier and getting the pressure off their nerves.

How did you identify NeoDisc as a product that might be a worthwhile acquisition for NuVasive?

We spend a lot of time scouring over what's going on in our marketplace, and the NeoDisc device was one that we saw presented several times. The timing was great for Pearsalls, in that the company was looking for a partner that would inject the appropriate capital to take the technology to the next level.

It was also good timing on our part. We were at a point at which we were investigating novel technologies, and we had an interest in being able to catapult things forward.

The other two products that you mentioned—the CerPass and the Lateral total disk replacement—were those also acquisitions?

No. Like the vast majority of our products, those were developed organically. Just about everything offered by NuVasive has been developed by our engineering and our marketing teams.

What percentage of revenues does NuVasive invest in R&D?

Right now we are in the high teens, as a percentage of revenue. I expect for us to stay in that mid-teen range for the next several years.

Meanwhile, NuVasive is also continuing to acquire. Earlier this year, the company acquired the Formagraft line of biologic bone void fillers from Radius Medical (Newport Beach, CA). Had you also been watching that product for some time?

We had been looking for about a year to find a new biologic that we could put into our armamentarium of products. We did not have a biologic component, so we saw the Formagraft line as an ideal product that we could use to add revenue on a per-procedure basis. We also made an investment in the manufacturing side of it, which is located in Taiwan.

Our inventory for the product is just beginning to scale up, and we believe there is an opportunity to achieve revenue in the short term, perhaps on the order of $4 million to $5 million this year.

But what excites us about the Formagraft technology is the potential for future applications of the material. Ultimately, it may be used as a coating for implants or even to deliver things like stem cells. There is a lot of upside to this technology.

And from a business perspective, it represented a good deal. Compared with the premiums that we've seen paid for a lot of other companies, we've done well with the acquisitions we've been able to complete, including both NeoDisc and Formagraft.

Some of the areas you mentioned take NuVasive away from traditional device areas and into the realms of biologicals and combination products. Does NuVasive watch those areas closely or invest in them in any way?

Well, we've started really paying attention to those areas. And the acquisition of the Formagraft line from Radius moves us a lot further in that direction. In the future, we expect to open up some full-fledged research in the area.

Seeing how well Medtronic Sofamor Danek has done in selling its bone morphogenic protein (BMP) product over the last several years, it's apparent that there are opportunities to take things to the next level by combining implants and biologics.


Spreading the Word

NuVasive has an impressive facility for training clinicians. How have the company's activities related to surgeon training affected the clinical adoption of the company's products overall?

The effects have been terrific in a lot of ways. First and foremost, the level of expertise that we have at our company is tremendous. Last year we trained close to 600 surgeons through our facility. So you can just imagine all the engineers and marketing folks that are there in the operating room, helping the surgeons.

Of course, with this kind of facility, every time we launch a new product we can work very closely with surgeons to perfect it pretty much on-site. And we think that's a very big competitive edge.

In general, surgeons walk away from their training here feeling enthusiastic and very comfortable about applying the technology. Consequently, our conversion rate has been quite high. Of the surgeons who have been trained here, about 70 to 75% apply the technology within the first 30 to 90 days. So we are very pleased with that.

The company also has an impressive clinical advisory board of orthopedic and neurological spine surgeons. How did you bring that board together? What role does the board play in helping you to develop future products, and driving the adoption of those products?

All of our products are developed in concert with surgeons, so the involvement of these advisers is critical. Fortunately, our team has been doing this for quite some time, and we have very strong track records with many of the country's top-ranked surgeons.

Those same surgeons have been attracted by the things that we do at NuVasive, one of which is to produce products faster than our competitors. We see that as an obligation as well as an edge in the marketplace. Surgeons absolutely love it when they can work with a company that looks to rapidly introduce new products.

Surgeons also love coming here. This is the finest spine surgery training facility in all of North America. None of the big companies have invested in anything like this. So again, it differentiates our service and our commitment to new product development.


Portfolio Development

NuVasive started with a core of intellectual property, but it is clearly building a significant portfolio around that. Can you describe what that portfolio looks like now?

NuVasive's patent portfolio has grown dramatically. The company now has 48 issued U.S. patents and 197 patents pending. Those have been developed mostly around our technologies in neurophysiology, fusion products, and our motion preservation implants. We recently also moved into cervical products.

Do you file on everything, or do you hold back some IP in the form of trade secrets?

No, we do not file on everything. We are very selective. But at the same time, we are making sure that we take a comprehensive view of how to protect and advance our portfolio.

In addition to the folks that have come on board here from Medtronic Sofamor Danek, Johnson & Johnson, and other key companies, we have had our own in-house patent counsel for about six years. We have built this team over the past several years to maintain control over our IP strategy and portfolio. That gives us the ability to clearly understand our market space, and to determine which products would be easy to design without direct patent conflicts of any sort, and which might be a lot tougher.

We always have a comprehensive view of our portfolio in mind. So we're not just throwing stuff up against the wall to see what will stick.

In addition to your in-house counsel, do you also work with an outside patent firm?

We do. We primarily use Fish & Richardson. We also use other firms, but we maintain the ability to perform patent prosecution in-house, which gives us significant strategic control over our patent portfolio.

And for all of these intellectual properties, is the vast majority of your development done internally?

That's correct. If we were to put a number on it, our organically developed intellectual properties would certainly be in the 90% range. Really, the only two NuVasive products developed externally are the NeoDisc and Formagraft products that we just acquired.


Reimbursement

Is NuVasive involved in activities to support coverage and payment decisions? Does the company have in-house staff focused on reimbursement?

We have resources that are dedicated to reimbursement, mostly in the form of consultants that we utilize. So, yes, we certainly are focused on this area.

What kinds of activities is the company involved in? For instance, has it been necessary for NuVasive to work with physicians in order to get reimbursement coverage through CMS or other third-party payers?

Right now, reimbursement is a pretty straightforward process for us. Our current products are all covered under existing reimbursement codes, so hospitals and surgeons don't need to hunt for new or different codes in order to obtain reimbursement.

Nevertheless, we do try to make sure that surgeons and hospitals understand the process and the appropriate codes. So we've put together packages that support our products in that way.

Even when reimbursement coding already exists, it sometimes seems that payment isn't quite a sure thing. Is CMS extraordinarily cautious about reimbursement in the spine area?

Last year, CMS essentially put out a rate increase of 5–6% for spine surgery. So that was very positive. This year, CMS has done the same thing again—about a 5–6% increase. So the climate is generally positive.

However, last year there was also a fair amount of discussion over what reimbursement for spine surgery might look like over the next couple of years. And it is increasingly clear that CMS is looking for more information with regard to outcomes.

Companies are doing everything necessary to satisfy clinical trial requirements and submit their products to FDA. But a number of products have received FDA clearance and made it to market, only to meet with resistance from CMS or other third-party payers. And the issue usually hinges on whether the company has demonstrated the superiority of its product. That standard is very different from the expectation of FDA studies, in which companies are expected to demonstrate equivalence or noninferiority.

That's what is changing right now. CMS is signaling that it is very important for companies to be aware of this new standard when it comes to their trials. Certainly, we are looking at the trials we're conducting, and we're making sure that the end points we have established address these issues.

So in the two-year follow-up period for the NeoDisc trial--and in other similar trials--do you include end points that you can present to CMS?

Yes. And I think the outcomes points are clearly there. But it's still tricky, because the end points of the trial were established in relation to the control device and procedure, which is a fusion plate. And what CMS is asking for is a demonstration of how, in general, the new product and procedure are superior.

So that's what we are doing. And I think everybody else is also moving in that direction.

It seems as though this could be tricky because it's a moving target. By the time you are actually presenting data to CMS, the standard of treatment may have changed quite a bit.

That's right. That's exactly right.

Do you think CMS provides enough reimbursement support to the field of spine surgery so that companies with new technologies will not become stalled as they seek to bring them to market?

CMS has certainly been supportive in the past, when it came to add-on payments for certain devices, for instance. Although the agency is saying that it will continue to be supportive in the future, it's not clear just how supportive it is going to be. So we'll see how that goes.

But I would say that most companies are trying to work within existing codes and come up with products that will have a strong economic benefit. In the case of our XLIF procedure, for example, we've conducted small studies in a couple of centers, and we've clearly demonstrated that the procedures can save hospitals about 20% compared with other technologies.

Those are the sorts of data that CMS and hospitals can become excited about. If a manufacturer can deliver new advantages and superior outcomes to patients—and can do it for the same amount of money as for other products, or less—then it's sure to have a winner. And that's clearly what we've done with XLIF.

So your studies incorporate end points relevant to both clinical and financial outcomes?

That's right.


The Exclusive Approach

NuVasive has invested heavily in developing its own direct sales force. Why did the company decide to make that move, and how is it working out?

We made this investment because there was no way for NuVasive to achieve robust long-term growth with a nonexclusive sales force.

We would like to continue growing our top line at the same kinds of rates we've had in recent quarters, as typified by 60% top-line growth last year, and 70% top-line growth for the first quarter of this year. We expect to be able to grow at rates like that for the foreseeable future.

Because it would be prohibitively expensive to start off with the expense of building a large exclusive sales force, almost every new company begins life with a nonexclusive sales force, just as NuVasive did. A nonexclusive sales force has the advantage of putting the company's products into the hands of more sales reps. But over time, that sales force will begin to carry multiple product lines, and the company will end up competing for the attention of both the sales reps and their customers. In short, a nonexclusive sales force just can't give an emerging company the sort of attention that it needs to significantly ramp sales.

So clearly, building our own exclusive sales force—which is about 50% direct and 50% exclusive distributors—has completely transformed our company. I felt very strongly about this strategy when we began down this path a few years ago, and we had absolutely no difficulty convincing people of the need to spend dollars on it. And we did. We have been very aggressive, and it has cost us millions of dollars. But I think the benefits of the strategy are already coming to pass.

We completed our transition to an exclusive sales force in June 2006, and we've seen nothing but record quarters ever since. Today, we have about 200 people in that sales force, and I think they are all very pleased to be representing NuVasive on a full-time basis.

Is the company using the same strategy overseas?

Overseas we are using a combination strategy. We are not immediately going to be able to get the kind of volume that would justify creating an exclusive sales force. But we will be using some direct sales folks in Germany.

What countries represent NuVasive's biggest overseas targets?

NuVasive's biggest market in Europe is in Germany and the Germanic language—speaking countries. So that's our primary area of emphasis. The UK and Australia are also major countries of focus for us.

Do you think the company will ever adopt a completely direct sales approach in those countries?

Possibly. We will have to see how it goes next year. But there is definitely an opportunity to go direct in certain countries, yes.


Competitive Financials

Has NuVasive grown to the point that it is now an acquisition target? Would that be a desirable outcome for the company?

We are not looking to sell the company, and we certainly don't want to be an acquisition target.

Over the next few years, we want to become a $500 million company. And with that, we want to maintain the culture that we've been proud to put together here. We want to offer the kind of products that we feel are critical to long-term success, and, in fact, we have spent considerable time developing a strategy to achieve these goals.

We have enjoyed being consistently ranked very highly by the financial community—from number three to number five—among the top innovators in the spine field. But what's really driving the NuVasive team is that everybody is enjoying the way the company is growing.

So NuVasive's success is not measured only by hitting financial targets. It's also seen in how the company has grown, its strong culture of high performance, its commitment to serving customers, and a lot of other factors that you've heard a million times from many different companies.

But I will tell you that people here really live it. NuVasive is a different kind of place from what most people are accustomed to. We are proud of that, and we want to perpetuate it.

Copyright ©2007 MX
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