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Bioresorbable Material Offers Elastomeric Alternative to PLA, PGA

Bioresorbable polymers are enabling the development of an increasing number of next-generation medical devices that benefit from the materials' ability to perform a specific function and then dissolve safely in the body. But the potential applications for bioresorbable and biodegradable polymers have been limited, to some extent, by the inherent properties of PLA and PGA, the most commonly used bioresorbable polymers.

Secant Medical is hoping to help push the boundaries of bioresorbable polymers, however, with the introduction of its Regenerez bioresorbable elastomer.

"[Regenerez] is very tough, elastic, elongates. This is a big differentiator," notes Brian Coffin, business development engineer at Secant Medical. "It's a bioresorbable that's elastomeric in nature instead of very stiff and tough like the PGAs and PLAs that have been in the market traditionally. So, this is meeting an unmet market need and filling a void for medical device manufacturers."

Engineered from poly(glycerol sebacate), the polymer features tunable mechanical properties, simulates the modulus of human tissue, promotes healing without inducing a harmful immune response, and is characterized by a versatile platform that allows for further modification, according to the company. 

The material is suited for use in a variety of cardiovascular, neurovascular, orthopedic, and surgical applications, including vascular grafts, bone regeneration, soft tissue engineering, cartilage, and prevention of visceroparietal peritoneal adhesion. 

For additional application examples and to see the material in action, check out the below video, sponsored by Secant Medical in collaboration with MD+DI.

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