No. 83 Edwards Lifesciences 

Innovation Premium: 41.3%

Edwards Lifesciences continues to make great strides in the lucrative transcatheter aortic valve market. Just this month, Edwards's Sapien 3 valve became the first TAVR valve to receive an expanded FDA indication that included patients with intermediate risk of dying or suffering serious complications during open-heart surgery, versus the previous indication for only high risk patients. 

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