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Bioprinting Advances Thanks to New Medical Print Head

Image courtesy of Brinter medical 3D printing bioprinting
The Finnish startup Brinter introduces a new line of print heads to minimize medical-grade material waste.

Finnish bioprinting startup, Brinter, known for its Brinter One modular system for printing multimaterial and highly complex tissue structures in 3D, is debuting the new extrusion-based Visco Bio medical print head. The heads were developed to offer dispensing material diversity, a continuous and precise printing for repeatability, and zero cross-contamination given the use of a single cartridge per material. The modular print heads also provide nearly zero dead volume, thanks to their dispensing geometry where a constant volume per revolution is always conveyed and precisely applied. 

Brinter One can print both stiff and soft materials, including liquids and hydrogels with living cells, bio-paste, metal with binder material, and plastic.

“The release of this print head means that basic requirements towards Good Manufacturing Practices (GMP) are met, for example, due to no cross-contamination with the use of a single cartridge per material, used together with the disinfecting blue light module we published in December,” explained Tomi Kalpio, CEO of Brinter, in a news release. “Likewise, researchers, pharma industry, and universities benefit from the repeatability of printing results being increased due to continuous and precise printing processes.” 

Kalpio noted in his remarks that the practical applications of the technology align with his company’s vision to improve quality of life by shortening and enhancing the productivity of the scientific discovery process and bio-manufacturing. “This pushes forward the ambition of printing human spare parts such as hearts and kidneys, as well as more personalized treatment through cancer research and drug testing,” he stated.

Brinter One is portable and designed for easy pack up and set up in a different lab or cleanroom in minutes.

Visco Bio was launched in close collaboration with Puredyne, which provided the innovative market technology. “Brinter is an innovative and strong partner for us, with whom we already have had a close relationship for some years" added Felix Gruber, Business Development Manager at Puredyne, in the release. The Puredyne print head with its involved progressive cavity technology enables a totally new precision in extrusion-based bioprinting. Moreover, our solution gives the operator the required process and material flexibility in the handling of low to high viscosity biomaterials." 

In February, Brinter announced its cooperation with LED Tailor to introduce a new disinfecting blue light feature embedded in its multimaterial 3D bioprinting solution. The system enables the safe production of tissue models and drugs and minimizes the need for separate cleanrooms, making bioprinters more portable and safe, according to the company.

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