Wounds Close with Blood Protein
A material spun from common blood protein could be used for wound sutures, large dressings, and antiadhesion membranes, such as those used in abdominal surgery. Researchers from Technion-Israel Institute of Technology have been working on the biological material. They believe the protein-based material would be less at risk of being rejected by the body and it would be less prone to scarring compared with wound materials currently on the market. The material is derived from globular protein bovine serum albumin. The protein is spun into thick mats using electrospinning, a technique that uses an electrical charge to pull and stretch liquid droplets into nanosized fibers. According to one report, many researchers have used the technique to spin fibers from organic materials, hoping to mimic the strength and elasticity of natural substances such as spider silk, for example. However, it has been a challenge to spin organic materials into stable threads, making it necessary to spin a blend of artificial and natural molecules. Most proteins adopt a coiled shape, which scientists attempt to straighten out by adding artificial molecules to the protein during electrospinning. The researchers found a way to break the protein's bonds and turn it into a linear polymer without using additional molecules to force it into a fibrous shape. The Technion researchers now plan to test the electrospinning technique on other proteins.
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