. A new compound combines chemical resistance with low-temperature properties. Xyfluor, developed by Greene, Tweed & Co. (Kulpsville, PA; 215/256-9521), provides a similar chemical resistance to that of traditional perfluoroelastomers. Unlike other elastomers, Xyfluor retains its flexibility at temperatures as low as –76š and as high as 450šF. The compound withstands steam autoclave sterilization and exposure, exhibits low sealing forces, and is compatible with common solvents such as dimethylsulfoxide (DMSO), acetone, and methyl ethyl ketone (MEK). Applications range from O-rings and T-seals to gaskets for microfluidics and closures for drug sampling.